Micro-Manipulation Techniques

Micro-manipulation techniques are highly advanced procedures used in Assisted Reproductive Technology (ART) to enhance fertilization success rates and improve embryo development. These techniques involve the microsurgical handling of eggs, sperm, and embryos, allowing for greater precision in fertility treatments such as Intracytoplasmic Sperm Injection (ICSI), assisted hatching, and embryo biopsy.

At DYU Advanced Fertility & Smart IVF Center, we utilize state-of-the-art micro-manipulation technologies to optimize fertility outcomes and ensure the highest standards in ART procedures.

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Types of Micro-Manipulation Techniques

1. Intracytoplasmic Sperm Injection (ICSI)

Direct injection of a single sperm into an egg using a fine micro-needle.
Used in cases of severe male infertility or low sperm count.
Enhances fertilization success rates in IVF cycles.

2. Laser-Assisted Hatching (LAH)

Utilizes laser precision technology to thin or open the embryo’s outer shell (zona pellucida).
Helps embryos hatch more easily and improves implantation rates in IVF.
Recommended for patients with previous IVF failures, advanced maternal age, or thick zona pellucida.

3. Embryo Biopsy for Genetic Testing (PGT)

Micro-surgical removal of a few cells from an embryo for genetic screening.
Used in Preimplantation Genetic Testing (PGT-A, PGT-M, PGT-SR) to ensure healthy embryo selection.
Helps prevent genetic disorders and increases the chances of a successful pregnancy.

4. Sperm & Oocyte Micro-Manipulation

Techniques such as sperm immobilization and oocyte rotation to optimize fertilization.
Ensures precise handling and positioning of gametes for successful ART treatments.

5. Blastocyst Collapsing for Vitrification

A technique used to improve embryo survival rates during freezing (cryopreservation).
Reduces intracellular water content, minimizing ice crystal formation and damage.

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